Article
MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD.
EBioMedicine - 1 Jul 2020
Meroni Marica, Longo Miriam, Fracanzani Anna L, Dongiovanni Paola
Abstract excerpt
Metabolic associated fatty liver disease (MAFLD) encompasses a broad spectrum of hepatic disorders, which include steatosis, nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis, that is a critical risk factor for hepatocellular carcinoma (HCC) development. Its pathogenesis is intertwined with obesity and type 2 diabetes (T2D). However, the predisposition to develop MAFLD is severely influenced by...
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