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Article

Inflammatory response mediates cross-talk with immune function and reveals clinical features in acute myeloid leukemia.

Bioscience reports - 27 May 2022

Zhong Fang-Min, Yao Fang-Yi, Liu Jing, Zhang Hai-Bin, Li Mei-Yong, Jiang Jun-Yao, Xu Yan-Mei, Yang Wei-Ming, Li Shu-Qi, Zhang Jing, Cheng Ying, Xu Shuai, Huang Bo, Wang Xiao-Zhong

Abstract excerpt

Accumulated genetic mutations are an important cause for the development of acute myeloid leukemia (AML), but abnormal changes in the inflammatory microenvironment also have regulatory effects on AML. Exploring the relationship between inflammatory response and pathological features of AML has implications for clinical diagnosis, treatment and prognosis evaluation. We analyzed the expression variation landscape...

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Identifiers

PMID: 35441668
DOI: 10.1042/BSR20220647
PMCID: PMC9093697

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