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Article

Anaplastic lymphoma kinase overexpression enhances aggressive phenotypic characteristics of endometrial carcinoma.

BMC cancer - 17 Aug 2023

Yokoi Ako, Nakamura Yusaku, Hashimura Miki, Oguri Yasuko, Matsumoto Toshihide, Nakagawa Mayu, Ishibashi Yu, Ito Takashi, Ohhigata Kensuke, Harada Youhei, Fukagawa Naomi, Saegusa Makoto

Abstract excerpt

BACKGROUND: Although anaplastic lymphoma kinase (ALK) is overexpressed in several primary solid tumor types, its role in endometrial carcinoma (Em Ca) remains unclear. METHODS: We evaluated expression of ALK and its related molecules in clinical samples consisting of 168 Em Ca tissues. We also used Em Ca cell lines to evaluate the functional role of ALK. RESULTS: Cytoplasmic ALK immunoreactivity in the absence of...

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Identifiers

PMID: 37592266
DOI: 10.1186/s12885-023-11144-2
PMCID: PMC10436652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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