Article
ILK-induced epithelial-mesenchymal transition promotes the invasive phenotype in adenomyosis.
Biochemical and biophysical research communications - 18 Mar 2018
Zhou Wenjun, Peng Zheng, Zhang Chun, Liu Shuangshen, Zhang Yi
Abstract excerpt
OBJECTIVE: Adenomyosis is a benign gynecological disease, characterized by the malignant biological behaviors of invasion and metastasis. ILK plays an important role in intercellular adhesion and triggers the process of EMT. In this study, we investigated the role of ILK-induced EMT in the pathogenesis of adenomyosis. METHODS: ILK and EMT markers including E-cadherin, N-cadherin and Vimentin have been detected...
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