Article
Functional role of ALK-related signal cascades on modulation of epithelial-mesenchymal transition and apoptosis in uterine carcinosarcoma.
Molecular cancer - 14 Feb 2017
Inoue H, Hashimura M, Akiya M, Chiba R, Saegusa M
Abstract excerpt
BACKGROUND: Anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase, is essentially and transiently expressed in the developing nervous system. Recently, the deregulated expression of full-length ALK has been observed in some primary solid tumors, but little is known about its involvement in the tumorigenesis of uterine carcinosarcomas (UCSs). Here we examined the functional role of the ALK gene in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.