Genetic Phenotypes of Alzheimer’s Disease: Mechanisms and Potential Therapy

Abstract excerpt

Abstract Years of intensive research has brought us extensive knowledge on the genetic and molecular factors involved in Alzheimer's disease (AD). In addition to the mutations in the three main causative genes of familial AD (FAD) including presenilins and amyloid precursor protein genes, studies have identified several genes as the most plausible genes for the onset and progression of FAD, such as triggering...

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