Article
Alteration of tumor suppressors changes the endometrial tumor spectrum.
EMBO molecular medicine - 11 Oct 2023
Mayo Lindsey D
Abstract excerpt
The most common gynecological cancer in Europe and the United States is endometrial. Like most cancers, early-stage endometrial cancer has a more favorable prognosis, while high-grade, including endometrioid and nonendometrioid, has the worst prognosis. In endometrioid human tumors, the tumor suppressor genes PTEN and p53 (Trp53) are frequently altered or lost, as identified in datasets from The Cancer Genome...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
