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Article

Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition.

Proceedings of the National Academy of Sciences of the United States of America - 17 Dec 2019

Cuevas Ileana C, Sahoo Subhransu S, Kumar Ashwani, Zhang He, Westcott Jill, Aguilar Mitzi, Cortez Jeremy D, Sullivan Stephanie A, Xing Chao, Hayes D Neil, Brekken Rolf A, Bae-Jump Victoria L, Castrillon Diego H

Abstract excerpt

Uterine carcinosarcoma is an aggressive variant of endometrial carcinoma characterized by unusual histologic features including discrete malignant epithelial and mesenchymal components (carcinoma and sarcoma). Recent studies have confirmed a monoclonal origin, and comprehensive genomic characterizations have identified mutations such as Tp53 and Pten However, the biological origins and specific combination of...

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Identifiers

PMID: 31772025
DOI: 10.1073/pnas.1911310116
PMCID: PMC6926017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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