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Article

Genetic alterations in endometrial cancer by targeted next-generation sequencing.

Experimental and molecular pathology - 1 Feb 2016

Chang Ya-Sian, Huang Hsien-Da, Yeh Kun-Tu, Chang Jan-Gowth

Abstract excerpt

Many genetic factors play important roles in the development of endometrial cancer. The aim of this study was to investigate genetic alterations in the Taiwanese population with endometrial cancer. DNA was extracted from 10 cases of fresh-frozen endometrial cancer tissue. The exomes of cancer-related genes were captured using the NimbleGen Comprehensive Cancer Panel (578 cancer-related genes) and sequenced using...

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Source

Identifiers

PMID: 26626801
DOI: 10.1016/j.yexmp.2015.11.026

Genes

PTEN
AKT2
ALK
ATM
BCL9
CTNNB1
ERBB2
FGFR2
FLT3
FOXO1
KIT
MSH2
MTOR
PDGFRA
PTCH1
PTPN11
TET2
TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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