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Article

Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study.

Cardiovascular toxicology - 1 Apr 2024

Shi Yi-Ming, Ou Dian, Li Jia-Ting, Bao Le, Liu Xiao-Dan, Zhang Wei, Ding Huang

Abstract excerpt

The aim of this study was to comprehensively assess the causal relationship between the overall genetic effect of circulating ApoE levels and panvascular lesions using newer genome-wide association data and two-sample bidirectional Mendelian randomization (MR) analysis. Two-way MR using single-nucleotide polymorphisms of circulating ApoE as instrumental variables was performed using the highest-priority...

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PMID: 38536640
DOI: 10.1007/s12012-024-09846-5

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