Article

The CXCR6/CXCL16 axis links inflamm-aging to disease severity in COVID-19 patients

2021-01-25

Abstract excerpt

Advancing age and chronic health conditions, significant risk factors for severe COVID-19, are associated with a pro-inflammatory state, termed inflamm-aging. CXCR6 + T cells are known to traffic to the lung and have been reported to increase with age. The ligand of CXCR6, CXCL16, is constitutively expressed in the lung and upregulated during inflammatory responses and the CXCR6/CXCL16 axis is associated with sev...

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Literature Corpus work: f777a68c-e7f3-521d-9a89-8b10a90d6d7c
DOI: 10.1101/2021.01.25.428125

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