Article
HIV-1 Drug Resistance among Treatment-Naïve Patients in Russia: Analysis of the National Database, 2006-2022.
Viruses - 18 Apr 2023
Kirichenko Alina, Kireev Dmitry, Lapovok Ilya, Shlykova Anastasia, Lopatukhin Alexey, Pokrovskaya Anastasia, Bobkova Marina, Antonova Anastasiia, Kuznetsova Anna, Ozhmegova Ekaterina, Shtrek Sergey, Sannikov Aleksej, Zaytseva Natalia, Peksheva Olga, Piterskiy Michael, Semenov Aleksandr, Turbina Galina, Filoniuk Natalia, Shemshura Andrey, Kulagin Valeriy, Kolpakov Dmitry, Suladze Aleksandr, Kotova Valeriya, Balakhontseva Lyudmila, Pokrovsky Vadim, Akimkin Vasiliy
Abstract excerpt
In Russia, antiretroviral therapy (ART) coverage has significantly increased, which, in the absence of routine genotyping testing, could lead to an increase in HIV drug resistance (DR). The aim of this study was to investigate the patterns and temporal trends in HIV DR as well as the prevalence of genetic variants in treatment-naïve patients from 2006 to 2022, using data from the Russian database (4481 protease...
Topics
- Humans
- Male
- HIV-1
- Anti-HIV Agents
- Drug Resistance, Viral
- HIV Infections
- HIV Seropositivity
- Mutation