Article
BRCA Mutation Patients: Are There Other Predisposing Factors for Ovarian Cancer Occurrence? A Multicenter Retrospective Study.
Gynecologic and obstetric investigation - 1 Jan 2024
Loizzi Vera, Mongelli Michele, Arezzo Francesca, Romagno Isabella, Cazzato Gerardo, Popescu Ondina, Legge Francesco, Trerotoli Paolo, Silvestris Erica, Kardhashi Anila, Cormio Gennaro
Abstract excerpt
OBJECTIVES: The objective of this multicenter retrospective study aimed to evaluate the association of clinical variables and the incidence of ovarian cancer in patients with BRCA 1-2 mutation carriers who underwent risk-reducing salpingo-oophorectomy (RRSO). DESIGN: Patients with a pathogenic mutation of BRCA 1-2 genes and with no evidence of disease are considered eligible. The exclusion criterion was the...
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