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BRCA Mutation Patients: Are There Other Predisposing Factors for Ovarian Cancer Occurrence? A Multicenter Retrospective Study.

Gynecologic and obstetric investigation - 1 Jan 2024

Loizzi Vera, Mongelli Michele, Arezzo Francesca, Romagno Isabella, Cazzato Gerardo, Popescu Ondina, Legge Francesco, Trerotoli Paolo, Silvestris Erica, Kardhashi Anila, Cormio Gennaro

Abstract excerpt

OBJECTIVES: The objective of this multicenter retrospective study aimed to evaluate the association of clinical variables and the incidence of ovarian cancer in patients with BRCA 1-2 mutation carriers who underwent risk-reducing salpingo-oophorectomy (RRSO). DESIGN: Patients with a pathogenic mutation of BRCA 1-2 genes and with no evidence of disease are considered eligible. The exclusion criterion was the...

Topics

Female
Humans
Breast Neoplasms
Causality
Genetic Predisposition to Disease
Mutation
Ovarian Neoplasms
Ovariectomy
Retrospective Studies
BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

BRCA2 Protein

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PMID: 38246147
DOI: 10.1159/000535012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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BRCA Mutation Patients: Are There Other Predisposing Factors for Ovarian Cancer Occurrence? A Multicenter Retrospective Study.PMID 38246147Read ↗

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The challenging screen detection of ovarian cancer in BRCA mutation carriers adhering to a 6-month follow-up program: results from a 6-years surveillance.Semantic proximity Read ↗

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Efficacy of risk-reducing salpingo-oophorectomy in BRCA1-2 variants and clinical outcomes of follow-up in patients with isolated serous tubal intraepithelial carcinoma (STIC).Semantic proximity Read ↗

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