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Genetically proxied lean mass and risk of Alzheimer’s disease: mendelian randomisation study

1 May 2023

Abstract excerpt

Objective: To examine whether genetically proxied lean mass is associated with risk of Alzheimer's disease. Design: Mendelian randomisation study. Setting: The UK Biobank study and genome wide association study meta-analyses of Alzheimer's disease and cognitive performance. Participants: Summary level genetic data from: 450 243 UK Biobank participants with impedance measures of lean mass and fat mass; an...

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PMID: 37564828
DOI: 10.1136/bmjmed-2022-000354

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