Article
Body mass index, genetic susceptibility, and Alzheimer's disease: a longitudinal study based on 475,813 participants from the UK Biobank.
Journal of translational medicine - 9 Sept 2022
Yuan Shiqi, Wu Wentao, Ma Wen, Huang Xiaxuan, Huang Tao, Peng MIn, Xu Anding, Lyu Jun
Abstract excerpt
BACKGROUND: The association between body mass index (BMI) and Alzheimer's disease (AD) remains controversial. Genetic and environmental factors are now considered contributors to AD risk. However, little is known about the potential interaction between genetic risk and BMI on AD risk. OBJECTIVE: To study the causal relationship between BMI and AD, and the potential interaction between AD genetic risk and BMI on...
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