Article
Body Mass Index and Risk of Alzheimer's Disease: A Mendelian Randomization Study of 399,536 Individuals.
The Journal of clinical endocrinology and metabolism - 1 Jul 2017
Nordestgaard Liv Tybjærg, Tybjærg-Hansen Anne, Nordestgaard Børge G, Frikke-Schmidt Ruth
Abstract excerpt
Context: Recently, data on 2,000,000 people established that low body mass index (BMI) is associated with increased risk of dementia. Whether this observational association reflects a causal effect remains to be clarified. Objective: We tested the hypothesis that there is a causal association between low BMI and high risk of Alzheimer's disease. Design, Setting, and Participants: Using a Mendelian randomization...
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