Integrative genomics analysis reveals a 21q22.11 locus contributing risk to COVID-19.

doi:10.1093/hmg/ddab125

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Integrative genomics analysis reveals a 21q22.11 locus contributing risk to COVID-19.

Human molecular genetics - 17 Jun 2021

Ma Yunlong, Huang Yukuan, Zhao Sen, Yao Yinghao, Zhang Yaru, Qu Jia, Wu Nan, Su Jianzhong

Abstract excerpt

The systematic identification of host genetic risk factors is essential for the understanding and treatment of coronavirus disease 2019 (COVID-19). By performing a meta-analysis of two independent genome-wide association summary datasets (N = 680 128), a novel locus at 21q22.11 was identified to be associated with COVID-19 infection (rs9976829 in IFNAR2-IL10RB, odds ratio = 1.16, 95% confidence...

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PMID: 33949668
DOI: 10.1093/hmg/ddab125
PMCID: PMC8136003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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