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Article

Genetically Predicted Insomnia in Relation to 14 Cardiovascular Conditions and 17 Cardiometabolic Risk Factors: A Mendelian Randomization Study.

Journal of the American Heart Association - 3 Aug 2021

Liu Xinhui, Li Chuanbao, Sun Xiaoru, Yu Yuanyuan, Si Shucheng, Hou Lei, Yan Ran, Yu Yifan, Li Mingzhuo, Li Hongkai, Xue Fuzhong

Abstract excerpt

Background This Mendelian randomization study aims to investigate causal associations between genetically predicted insomnia and 14 cardiovascular diseases (CVDs) as well as the potential mediator role of 17 cardiometabolic risk factors. Methods and Results Using genetic association estimates from large genome-wide association studies and UK Biobank, we performed a 2-sample Mendelian randomization analysis to...

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Identifiers

PMID: 34315237
DOI: 10.1161/JAHA.120.020187
PMCID: PMC8475657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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