Article
Identifying depression's genetic role as a precursor to sepsis and increased mortality risk: Comprehensive insights from mendelian randomization analysis.
PloS one - 1 Jan 2024
Zhou Qingyi, Shen Qili, Chen Xiaohua, Yang Lichun, Ma Qiang, Chu Liang
Abstract excerpt
BACKGROUND: Previous retrospective studies have shown a correlation between depression and increased risk of infections, including a moderate rise in sepsis likelihood associated with severe depression and anxiety. To investigate the potential causal links between depression, sepsis, and mortality risks, while considering confounding factors, we employed a Mendelian randomization (MR) approach. METHODS: In this...
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