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Article

Polycystic kidneys: interaction of notch and renin.

Clinical science (London, England : 1979) - 14 Aug 2023

Daniel Emily A, Sommer Nicole A, Sharma Madhulika

Abstract excerpt

Polycystic kidney disease (PKD) is a developmental disorder, which either manifests in early childhood or later in life, depending on the genetic mutation one harbors. The mechanisms of cyst initiation are not well understood. Increasing literature is now suggesting that Notch signaling may play a critical role in PKD. Activation of Notch signaling is important during nephrogenesis and slows down after...

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Identifiers

PMID: 37553961
DOI: 10.1042/CS20230023
PMCID: PMC11132639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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