Article
Notch in the kidney: development and disease.
The Journal of pathology - 1 Jan 2012
Sirin Yasemin, Susztak Katalin
Abstract excerpt
Notch signalling is a highly conserved cell-cell communication mechanism that regulates development, tissue homeostasis, and repair. Within the kidney, Notch has an important function in orchestrating kidney development. Recent studies indicate that Notch plays a key role in establishing proximal epithelial fate during nephron segmentation as well as the differentiation of principal cells in the renal collecting...
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