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Article

Downregulation of Krüppel‐like factor 14 accelerated cellular senescence and aging

8 Aug 2023

Abstract excerpt

Aging has been considered as a risk factor in many diseases, thus, comprehensively understanding the cellular and molecular mechanisms of delayed aging is important. Here we investigated whether Krüppel-like factor 14 (KLF14) is a suppressor of cellular senescence and aging. In our research, KLF14 levels significantly decreased not only in the lymphocytes of healthy people but also in the cells and tissues of...

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PMID: 37551728
DOI: 10.1111/acel.13950

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