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Article

METTL14 Regulates Intestine Cellular Senescence through m6A Modification of Lamin B Receptor.

Oxidative medicine and cellular longevity - 1 Jan 2022

Zhang Zizhen, Xue Meng, Chen Jingyu, Wang Zhuo, Ju Fangyu, Ni Jiaojiao, Sun Jiawei, Wu Haoyue, Zheng Huimei, Lou Ziwei, Zhang Yawen, Yang Xiaohang, Chen Shujie, Xi Yongmei, Wang Liangjing

Abstract excerpt

N-6-Methyladenosine (m6A) modification is involved in multiple biological processes including aging. However, the regulation of m6A methyltransferase-like 14 (METTL14) in aging remains unclear. Here, we revealed that the level of m6A modification and the expression of METTL14 were particularly decreased in the intestine of aged mice as compared to young mice. Similar results were confirmed in Drosophila...

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Identifiers

PMID: 36578521
DOI: 10.1155/2022/9096436
PMCID: PMC9792243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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