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Article

Genetic liability to frailty in relation to functional outcome after ischemic stroke.

International journal of stroke : official journal of the International Stroke Society - 1 Jan 2024

Cai Huan, Zhang Hao, Liang Jialin, Liu Zhonghua, Huang Guozhi

Abstract excerpt

BACKGROUND: Frailty appears to be associated with unfavorable prognosis after stroke in observational studies, but the causality remains largely unknown. AIMS: The aim of this study is to investigate the potential causal effect of frailty on functional outcome at 3 months after ischemic stroke using the Mendelian randomization (MR) framework. METHODS: Genetic instruments for frailty index were identified in a...

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PMID: 37542426
DOI: 10.1177/17474930231194676

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