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Article

LRRC15 expression indicates high level of stemness regulated by TWIST1 in mesenchymal stem cells

23 May 2023

Abstract excerpt

Mesenchymal stem cells (MSCs) are used as a major source for cell therapy, and its application is expanding in various diseases. On the other hand, reliable method to evaluate quality and therapeutic properties of MSC is limited. In this study, we focused on TWIST1 that is a transcription factor regulating stemness of MSCs and found that the transmembrane protein LRRC15 tightly correlated with the expression of...

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PMID: 37534184
DOI: 10.1016/j.isci.2023.106946

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