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Article

Emerging role of Twist1 in fibrotic diseases

5 Jan 2018

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is a pathological process that occurs in a variety of diseases, including organ fibrosis. Twist1, a basic helix-loop-helix transcription factor, is involved in EMT and plays significant roles in various fibrotic diseases. Suppression of the EMT process represents a promising approach for the treatment of fibrotic diseases. In this review, we discuss the roles and the...

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PMID: 29314610
DOI: 10.1111/jcmm.13465

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