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Article

Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24

5 Nov 2013

Abstract excerpt

Twist2 is a highly conserved basic helix-loop-helix transcription factor that plays a critical role in embryogenesis. Recent evidence has revealed that aberrant Twist2 expression contributes to tumor progression; however, the role of Twist2 in human hepatocellular carcinoma (HCC) and its underlying mechanisms remain undefined. In this report, we demonstrate that Twist2 is overexpressed in human HCC tumors. We...

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PMID: 24193512
DOI: 10.1093/carcin/bgt364

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