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Article

Apolipoprotein E (ApoE) Rescues the Contractile Smooth Muscle Cell Phenotype in Popliteal Artery Aneurysm Disease.

Biomolecules - 4 Jul 2023

Pauli Jessica, Reisenauer Tessa, Winski Greg, Sachs Nadja, Chernogubova Ekaterina, Freytag Hannah, Otto Christoph, Reeps Christian, Eckstein Hans-Henning, Scholz Claus-Jürgen, Maegdefessel Lars, Busch Albert

Abstract excerpt

Popliteal artery aneurysm (PAA) is the most frequent peripheral aneurysm, primarily seen in male smokers with a prevalence below 1%. This exploratory study aims to shed light on cellular mechanisms involved in PAA progression. Sixteen human PAA and eight non-aneurysmatic popliteal artery samples, partially from the same patients, were analyzed by immunohistochemistry, fluorescence imaging, Affymetrix mRNA...

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Share to Aortic Aneurysm, Abdominal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myocytes, Smooth Muscle

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Source

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Identifiers

PMID: 37509110
DOI: 10.3390/biom13071074
PMCID: PMC10377618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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