Article
From genetics to response to injury: vascular smooth muscle cells in aneurysms and dissections of the ascending aorta.
Cardiovascular research - 15 Mar 2018
Michel Jean-Baptiste, Jondeau Guillaume, Milewicz Dianna M
Abstract excerpt
Vascular smooth muscle cells (vSMCs) play a crucial role in both the pathogenesis of Aneurysms and Dissections of the ascending thoracic aorta (TAAD) in humans and in the associated adaptive compensatory responses, since thrombosis and inflammatory processes are absent in the majority of cases. Aneurysms and dissections share numerous characteristics, including aetiologies and histopathological alterations: vSMC...
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