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Article

Phenotype-genotype relationships in Xenopus sox9 crispants provide insights into campomelic dysplasia and vertebrate jaw evolution.

Development, growth & differentiation - 1 Oct 2023

Hossain Nusrat, Igawa Takeshi, Suzuki Makoto, Tazawa Ichiro, Nakao Yuta, Hayashi Toshinori, Suzuki Nanoka, Ogino Hajime

Abstract excerpt

Since CRISPR-based genome editing technology works effectively in the diploid frog Xenopus tropicalis, a growing number of studies have successfully modeled human genetic diseases in this species. However, most of their targets were limited to non-syndromic diseases that exhibit abnormalities in a small fraction of tissues or organs in the body. This is likely because of the complexity of interpreting the...

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PMID: 37505799
DOI: 10.1111/dgd.12884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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