Article
Utilizing the chicken as an animal model for human craniofacial ciliopathies.
Developmental biology - 15 Jul 2016
Schock Elizabeth N, Chang Ching-Fang, Youngworth Ingrid A, Davey Megan G, Delany Mary E, Brugmann Samantha A
Abstract excerpt
The chicken has been a particularly useful model for the study of craniofacial development and disease for over a century due to their relatively large size, accessibility, and amenability for classical bead implantation and transplant experiments. Several naturally occurring mutant lines with craniofacial anomalies also exist and have been heavily utilized by developmental biologist for several decades. Two of...
Topics
- Abnormalities, Multiple
- Animals
- Animals, Genetically Modified
- Cell Cycle Proteins
- Cerebellum
- Chick Embryo
- Chickens
- Ciliopathies
- Craniofacial Abnormalities
- Disease Models, Animal
- Eye Abnormalities
- Genes, Lethal
- Genetic Association Studies