Article

Generation of a new <i>six1</i> -null line in <i>Xenopus tropicalis</i> for study of development and congenital disease

2021-07-30

Abstract excerpt

<h4>ABSTRACT</h4> The vertebrate Six ( S ine oculis homeobo x ) family of homeodomain transcription factors play critical roles in the development of several organs. Six1 plays a central role in cranial placode development, including the precursor tissues of the inner ear, as well as other cranial sensory organs and the kidney. In humans, mutations in SIX1 underlie some cases of branchio-oto-renal syndrome (BO...

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Literature Corpus work: 56fb5efe-2fbe-552e-b772-5e7ab354068a
DOI: 10.1101/2021.07.30.454496

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