Article
Genetics of cannabis use in opioid use disorder: A genome-wide association and polygenic risk score study.
PloS one - 1 Jan 2023
Hillmer Alannah, Chawar Caroul, Lamri Amel, Hudson Jacqueline, Kapczinski Flavio, Minuzzi Luciano, Marsh David C, Thabane Lehana, Paterson Andrew D, Samaan Zainab
Abstract excerpt
BACKGROUND: Individuals with an Opioid Use Disorder (OUD) have increased rates of cannabis use in comparison to the general population. Research on the short- and long-term impacts of cannabis use in OUD patients has been inconclusive. A genetic component may contribute to cannabis cravings. AIMS: Identify genetic variants associated with cannabis use through Genome-wide Association Study (GWAS) methods and...
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