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Article

DSM-5 cannabis use disorder: a phenotypic and genomic perspective.

Drug and alcohol dependence - 1 Jan 2014

Agrawal Arpana, Lynskey Michael T, Bucholz Kathleen K, Kapoor Manav, Almasy Laura, Dick Danielle M, Edenberg Howard J, Foroud Tatiana, Goate Alison, Hancock Dana B, Hartz Sarah, Johnson Eric O, Hesselbrock Victor, Kramer John R, Kuperman Samuel, Nurnberger John I, Schuckit Marc, Bierut Laura J

Abstract excerpt

BACKGROUND: We explore the factor structure of DSM-5 cannabis use disorders, examine its prevalence across European- and African-American respondents as well as its genetic underpinnings, utilizing data from a genome-wide study of single nucleotide polymorphisms (SNPs). We also estimate the heritability of DSM-5 cannabis use disorders explained by these common SNPs. METHODS: Data on 3053 subjects reporting a...

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Identifiers

PMID: 24315570
DOI: 10.1016/j.drugalcdep.2013.11.008
PMCID: PMC3943464

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