Article

Genetics of cannabis ever-use and frequency across ancestries implicate novel loci and brain-specific biology

2026-04-27

Abstract excerpt

Cannabis use is widespread, with genetic differences partly explaining variation in individual patterns of use. We performed the largest-to-date genome-wide association study (GWAS) meta-analysis of cannabis ever-use (N=736,322, 76% European ancestry) and various measures of frequency of use (N=269,160 cannabis users, 84% European ancestry). We identified 54 independent genome-wide significant loci for ever-use an...

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Literature Corpus work: 97c317ed-07aa-52af-a15e-524ba4da1f95
DOI: 10.64898/2026.04.25.26351611

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