Article
Cerebellar EEG source localization reveals age-related compensatory activity moderated by genetic risk for Alzheimer's disease.
Psychophysiology - 1 Dec 2023
Paitel Elizabeth R, Nielson Kristy A
Abstract excerpt
The apolipoprotein-E (APOE) ε4 allele is the greatest genetic risk factor for late-onset Alzheimer's disease (AD), but alone it is not sufficiently predictive. Because neuropathological changes associated with AD begin decades before cognitive symptoms, neuroimaging of healthy, cognitively intact ε4 carriers (ε4+) may enable early characterization of patterns associated with risk for future decline. Research in...
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