Article
Inhibitory P300 subprocesses and neural compensation in genetic risk for Alzheimer's disease: The case for temporal-spatial principal component analysis.
Psychophysiology - 1 Dec 2024
Paitel Elizabeth R, Nielson Kristy A
Abstract excerpt
The P300 event-related potential (ERP) is widely investigated in cognitive neuroscience, including related to aging, with smaller amplitudes and delayed latency consistently reported in Alzheimer's disease (AD). Given that AD-related neurological changes begin years before symptom onset, ERPs in asymptomatic elders with AD risk may characterize early changes. ERPs are seldom studied in this population. Yet,...
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