The balance of the immune system between HLA-G and NK cells in unexplained recurrent spontaneous abortion and polymorphisms analysis.

doi:10.1007/s12026-015-8771-9

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Article

The balance of the immune system between HLA-G and NK cells in unexplained recurrent spontaneous abortion and polymorphisms analysis.

Immunologic research - 1 Jun 2016

Arjmand Fateme, Ghasemi Nasrin, Mirghanizadeh Seyed Ali, Samadi Morteza

Abstract excerpt

Human leukocyte antigen (HLA)-G is involved in immunoregulatory processes and particularly in pathogenesis of inflammatory disorders such as recurrent spontaneous abortions (RSA). The purpose of the current study was to examine whether two single nucleotide polymorphisms (SNPs) of HLA-G gene (rs1736936 and HLA-G*0105N) influence susceptibility to recurrent spontaneous abortion. Genomic DNA from 117 RSA patients...

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PMID: 26754761
DOI: 10.1007/s12026-015-8771-9

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