Article
Evaluation of HLA-G 14-bp ins/del and +3142G>C polymorphisms with susceptibility to recurrent spontaneous abortion.
Taiwanese journal of obstetrics & gynecology - 1 Jun 2017
Hashemi Mohammad, Mokhtari Mojgan, Khazaeian Safura, Bahari Gholamreza, Rezaei Maryam, Nakhaee Alireza, Taheri Mohsen
Abstract excerpt
OBJECTIVE: HLA-G is critically important for successful implantation during pregnancy. Increasing evidence supposed that HLA-G plays a key role in tolerance of the semi-allogeneic graft in pregnancy by inhibiting the cytotoxic functions of T and NK cells. The present study aimed to evaluate the impact of HLA-G rs1063320 (+3142G>C) and 14-bp insertion (ins)/deletion (del) polymorphisms on recurrent spontaneous...
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