Article
HLA-G polymorphisms in couples with recurrent spontaneous abortions.
Tissue antigens - 1 Aug 2002
Hviid T V, Hylenius S, Hoegh A M, Kruse C, Christiansen O B
Abstract excerpt
The etiology of a fraction of recurrent spontaneous abortions (RSA) may involve immunological mechanisms. Aberrant profiles of Th1 and Th2 cytokines have been observed which are not present in uncomplicated pregnancies. Studies of classical HLA class I and II antigens in relation to RSA have not been conclusive. Furthermore, these antigens are not expressed in the placenta with the exception of HLA-C. However,...
Topics
- Abortion, Habitual
- Exons
- Female
- Gene Frequency
- Genotype
- HLA Antigens
- HLA-G Antigens
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Male
- Polymorphism, Genetic
