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Article

Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.

Scientific reports - 25 Jul 2023

Yazar Volkan, Kühlwein Julia K, Knehr Antje, Grozdanov Veselin, Ekici Arif B, Ludolph Albert C, Danzer Karin M

Abstract excerpt

Epigenetic remodeling is emerging as a critical process for several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Genetics alone fails to explain the etiology of ALS, the investigation of the epigenome might therefore provide novel insights into the molecular mechanisms of the disease. In this study, we interrogated the epigenetic landscape in peripheral blood mononuclear cells...

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Identifiers

PMID: 37491426
DOI: 10.1038/s41598-023-38684-8
PMCID: PMC10368635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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