Article

Impaired ATF3 Signaling Involves SNAP25 in SOD1 Mutant ALS Patients

2023-03-14

Abstract excerpt

Epigenetic remodeling is emerging as a critical process for several neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS). Genetics alone fails to explain the etiology of ALS, the investigation of the epigenome might therefore provide novel insights into the molecular mechanisms of the disease. In this study, we interrogated the epigenetic landscape in peripheral blood mononuclear cells (PBMCs)...

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Literature Corpus work: c24ce3ba-0494-551d-aa0d-5e0006cb7002
DOI: 10.21203/rs.3.rs-2672952/v1

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