Article
ALS and FTD: an epigenetic perspective.
Acta neuropathologica - 1 Oct 2016
Belzil Veronique V, Katzman Rebecca B, Petrucelli Leonard
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two fatal neurodegenerative diseases seen in comorbidity in up to 50 % of cases. Despite tremendous efforts over the last two decades, no biomarkers or effective therapeutics have been identified to prevent, decelerate, or stop neuronal death in patients. While the identification of multiple mutations in more than two dozen genes elucidated...
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