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Article

Exploring the causal relationship between COPD and AKI: A bidirectional Mendelian randomization approach.

Medicine - 13 Feb 2026

Ma Hongchuang, Zhou Fangfang, Luo Qun

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) and acute kidney injury (AKI) are significant public health burdens, and emerging observational studies have suggested a potential link between them. However, causality remains unclear. This study aimed to investigate the causal relationship between COPD and AKI using two-sample Mendelian randomization (MR) analyses. We utilized 11 independent single-nucleotide...

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Share to Acute Kidney Injury
Share to Causality
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

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Identifiers

PMID: 41686622
DOI: 10.1097/MD.0000000000047337
PMCID: PMC12908769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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