Article
Causal associations of brain structure with bone mineral density: a large-scale genetic correlation study.
Bone research - 20 Jul 2023
Guo Bin, Wang Chao, Zhu Yong, Liu Zhi, Long Haitao, Ruan Zhe, Lin Zhangyuan, Fan Zhihua, Li Yusheng, Zhao Shushan
Abstract excerpt
In this study, we aimed to investigate the causal associations of brain structure with bone mineral density (BMD). Based on the genome-wide association study (GWAS) summary statistics of 1 325 brain imaging-derived phenotypes (BIDPs) of brain structure from the UK Biobank and GWAS summary datasets of 5 BMD locations, including the total body, femoral neck, lumbar spine, forearm, and heel from the GEFOS...
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