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Article

Casual associations between brain structure and sarcopenia: A large-scale genetic correlation and mendelian randomization study.

Aging cell - 1 Oct 2024

Yang Guang, Xie Wenqing, Li Bin, Zhao Guihu, Li Jinchen, Xiao Wenfeng, Li Yusheng

Abstract excerpt

Sarcopenia presenting a critical challenge in population-aging healthcare. The elucidation of the interplay between brain structure and sarcopenia necessitates further research. The aim of this study is to explore the casual association between brain structure and sarcopenia. Linkage disequilibrium score regression (LDSC) was conducted to estimate the genetic correlations; MR was then performed to explore the...

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Identifiers

PMID: 38881464
DOI: 10.1111/acel.14252
PMCID: PMC11464103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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