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Article

TERT promoter mutation subtypes and survival in stage I and II melanoma patients.

International journal of cancer - 1 Mar 2019

Andrés-Lencina Juan J, Rachakonda Sivaramakrishna, García-Casado Zaida, Srinivas Nalini, Skorokhod Alexander, Requena Celia, Soriano Virtudes, Kumar Rajiv, Nagore Eduardo

Abstract excerpt

Mutations within the promoter of gene encoding telomerase reverse transcriptase subunit are frequent in many cancers including melanoma. Previously, the TERT promoter mutations were shown to associate with markers of poor outcome and reduced survival in patients with primary melanoma. In this study, we investigated the impact of the subtypes of TERT mutations on disease-free and melanoma-specific survival in 287...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Membrane Proteins

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Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 30070694
DOI: 10.1002/ijc.31780

Genes

TERT
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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