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The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study

30 Jun 2023

Abstract excerpt

Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood. Methods: To explore the molecular profile of AD and aged platelets, we investigated platelet activation (i.e., CD62P expression), proteome and transcriptome in AD patients, non-demented elderly, and young individuals...

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PMID: 37457829
DOI: 10.3389/fmolb.2023.1196083

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