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Article

A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype.

Acta neuropathologica - 1 Nov 2014

Veitinger Michael, Oehler Rudolf, Umlauf Ellen, Baumgartner Roland, Schmidt Georg, Gerner Christopher, Babeluk Rita, Attems Johannes, Mitulovic Goran, Rappold Eduard, Lamont John, Zellner Maria

Abstract excerpt

Alzheimer's disease (AD), a multifactorial neurodegenerative condition caused by genetic and environmental factors, is diagnosed using neuropsychological tests and brain imaging; molecular diagnostics are not routinely applied. Studies have identified AD-specific cerebrospinal fluid (CSF) biomarkers but sample collection requires invasive lumbar puncture. To identify AD-modulated proteins in easily accessible...

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Identifiers

PMID: 25248508
DOI: 10.1007/s00401-014-1341-8
PMCID: PMC4201753

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