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Article

Association of Polygenic Score With Tumor Molecular Subtypes in Papillary Thyroid Carcinoma.

The Journal of clinical endocrinology and metabolism - 21 Dec 2023

Wang Jennifer R, Zafereo Mark E, Wang Wenyi, Joshu Corinne, Ray Debashree

Abstract excerpt

CONTEXT: Genome-wide association studies have identified germline variants associated with elevated PTC risk. It is also known that somatic driver mutations contribute to PTC development and as such PTCs can be further categorized into different molecular subtypes based on their somatic alterations. However, it remains unknown whether identified germline variants predictive of PTC risk are associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37453101
DOI: 10.1210/clinem/dgad407

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